VSL#3® Capsules
VSL#3® Capsules
The #1 gastroenterologist-recommended multi-strain probiotics brand†
VSL#3® capsules are a gold standard in probiotics – trusted by healthcare professionals and patients for the dietary management of GI conditions and to support microbiota balance and digestive well-being.
- Stored and shipped cold to preserve potency
- 8 complementary probiotic strains from 3 genera
- Formulated for the dietary management of IBS and ulcerative colitis
BUNDLE & SAVE
Couldn't load pickup availability
More Than a Probiotic.A Powerful Medical Food.
Pioneers in Probiotics.Leaders in Gut Health.
VSL#3®is an ultra-high-potency probiotic medical food — and the #1 gastroenterologist-recommended multi-strain probiotics brand.†Developed for people with serious gastrointestinal conditions, it’s trusted by healthcare professionals and customers alike for its scientific foundation, clinical credibility, and unwavering quality.
Built on Science.Proven in Practice.
Driven by research — not marketing trends — VSL#3®is trusted in clinical care for the dietary management of specific gastrointestinal conditions. It continues to set the standard for potency, consistency, and reliability in probiotic therapy.
Ultra-High-Potency.Guaranteed.
VSL#3®products deliver between 112.5 billion and 900 billion live bacteria per serving, depending on the formulation. Unlike many probiotics that only promise potency at the time of manufacture, VSL#3®guarantees potency through expiration when stored as directed.
Clinically Researched Formulas.Real-World Results.
Each VSL#3®product combines 8 well-characterized probiotic strains from 3 genera to help maintain a balanced intestinal microbiota and support digestive health. The VSL#3®family is specially designed for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and pouchitis.
Why Doctors Trust VSL#3®
VSL#3® Is Scientifically Formulated For The Dietary Management of IBS
Doctor Recommended
In a 2002 survey of gastroenterologists, 93% reported that IBS patients were satisfied with VSL#3.¹
The most frequently observed benefits:
- Less bloating
- Reduced pain
- Better stool consistency and frequency
- Overall symptom improvement
Clinically Studied and FODMAP Friendly Certified for the Dietary Management of IBS
In a 2021 clinical study, VSL#3® showed outcomes comparable to those achieved with a low FODMAP diet² — a commonly recommended but restrictive approach. Because VSL#3® is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.
It’s What’s on the Inside
Our unique8-strain formulationis designed so each strain complements the others, helping maintain a balanced gut microbiota. Billions of live, beneficial bacteria work together to support digestive health.
-
Bifidobacterium
Bifidobacterium breve,Bifidobacterium lactis(previously classified as B.infantis), Bifidobacterium lactis(previously classified as B.longum)
-
Lactobacillus
Lactobacillus acidophilus,Lactobacillus helveticus(previously classified as L.delbrueckii subsp. bulgaricus),Lactobacillus paracasei,Lactobacillus plantarum
-
Streptococcus
Streptococcus thermophilus
VSL#3® Capsules:Clean Ingredients. Verified Quality.
Free From Common Irritants:
- Dairy-Free
- Gluten-Free
- Soy-Free
- Nut-Free
- No GMOs
- Vegan
Certified for Peace of Mind:
- FODMAP Friendly Certified
- Halal Certified
- Kosher Certified
-
Dairy-Free
-
Gluten-Free
-
Soy-Free
-
Nut-Free
-
Vegan
-
No GMOs
VSL#3" Benefits:
A Clinically Studied Medical Food
VSL#3® is a medical-grade formulation supported byclinical research.
Ultra-High Potency, Guaranteed
Contains 112.5 billion live bacteria (CFU) per capsule-an ultra-high-potency formula designed to keep itslabeled potency through expiration when stored underrecommended conditions.
Multi-Strain
8 complementary strains from 3 different genera.
Shipped Cold for Maximum Potency
VSL#3® is shipped cold from our facility to your door to help preserve potency and ensure live probiotics arrive active and effective. Every order is packaged in recyclable, insulated materials with reusable ice packs to maintain optimal temperature control and reduce waste.
-
Refrigerated Supply Chain:
Cold from production to delivery.
-
ClimaCell® Packaging:
Sustainably insulated and 100% curbside recyclable.
-
Strain Potency Preserved:
Live probiotics that stay active through expiration when stored as directed.
FAQs
What is VSL#3®?
What is VSL#3®?
VSL#3®is an ultra-high-potency probiotic medical food intended for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and an ileal pouch (pouchitis).
How should I store VSL#3®?
How should I store VSL#3®?
VSL#3®should be stored under refrigeration at 36–46°F (2–8°C) to preserve potency. It can remain at room temperature for up to 2 weeks without reducing effectiveness.
What is a Medical Food?
What is a Medical Food?
Medical foods are formulated for the dietary management of diseases or conditions with distinctive nutritional needs that cannot be met by diet alone. Unlike dietary supplements, medical foods are intended for use under a healthcare provider's supervision.
How does VSL#3® compare to a Low FODMAP diet for IBS management?
How does VSL#3® compare to a Low FODMAP diet for IBS management?
In a 2021 clinical study, VSL#3®demonstrated dietary management outcomes in people with IBS comparable to those achieved with a low FODMAP diet¹ — a commonly recommended but restrictive approach. Because VSL#3®is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.
1Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291.
How are VSL#3® and VSL4® Gut different?
How are VSL#3® and VSL4® Gut different?
Although both products contain the same 8 probiotic strains, they are formulated and labeled for different purposes. VSL#3®is a refrigerated, ultra-high-potency probiotic medical food for the dietary management of specific GI conditions. VSL4®Gut is a probiotic supplement designed to support digestive comfort, regularity, and overall gut health.*
Important information
Safety Information
Safety Information
As a probiotic medical food, VSL#3® is intended to be used under medical supervision. VSL#3® IS THE #1 GASTROENTEROLOGIST-RECOMMENDED MULTI-STRAIN PROBIOTICS BRAND†. VSL#3® is a refrigerated, high-potency probiotic medical food intended for the dietary management of IBS, ulcerative colitis, and pouchitis. It is high-potency (112.5B to 900B CFU) and contains eight complementary probiotic strains from three different genera. VSL#3® is dairy-free, soy-free, gluten-free, non-GMO, nut-free, Vegan, Kosher and Halal certified. †ProVoice® Surveys. 1Data on File. 3https://doi.org/10.2196/30291.
Ingredients
Ingredients
Strains: Streptococcus thermophilus, Bifidobacterium breve, Bifidobacterium lactis (previously classified as B. longum), Bifidobacterium lactis (previously classified as B. infantis), Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus helveticus (previously classified as L. delbrueckii subsp. bulgaricus) Other Ingredients: Vegetal capsule (hydroxypropyl methylcellulose), cornstarch, magnesium stearate, silicon dioxide, stearic acid, microcrystalline cellulose
Directions
Directions
Instructions: VSL#3® capsules can be consumed with a cold, non-carbonated beverage. However, they should not be consumed with hot beverages or foods, as high heat inactivates the live bacteria. Storage: VSL#3® should be stored under refrigeration (36-46°F) but can be kept at room temperature (77°F) for up to 2 weeks without any noticeable loss in potency. Dosage: Take as directed by your physician (usual adult dosage is 2 capsules as needed, up to 4 times a day).
Legal Disclaimer
Legal Disclaimer
Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.