VSl® Probiotics: A Legacy of Science in Every Strain.
Building on the trusted heritage of VSL#3®, VSL®Probiotics now includes innovative supplements like VSL4®, designed for everyday wellness.
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Trusted worldwide
A legacy built on trust andexpertise.
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Rooted in science
Guided by probiotic research.
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Commitment to quality
Ensuring potency andreliability.
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Designed for diverse needs
Supporting gut and women'shealth.
A Gold Standard in Probiotics
- A powerful probiotic medical food
- The #1 gastroenterologist-recommended multi-strain probiotics brand†
- Ultra-high-potency — guaranteed through expiration when stored as recommended.
- 8 complementary probiotic strains from 3 different genera.
- Used in clinical practice and supported by clinical and scientific research.
Science Over Hype.Purpose Over Promises.
Built on the legacy of VSL#3®— a probiotic trusted by healthcare professionals and recognized for its scientific rigor — VSL® Probiotics continues to advance microbiome science through targeted, high-quality formulations that support both clinical dietary management and everyday wellness.
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Committed to Potency
Potent probiotic formulations guaranteed tomaintain labeled CFU counts throughexpiration.
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Designed for Viability
Carefully designed formulations that helpsafeguard live bacteria from production todelivery.
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Science-Led Strain Selection
Thoughtfully formulated with complementaryprobiotic strains chosen for function andpurpose.
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A Legacy of Expertise
A probiotic heritage recognized for itsconsistency, credibility, and professionaltrust.
VSL#3® Capsules:Clean Ingredients. Verified Quality.
Free From Common Irritants:
- Dairy-Free
- Gluten-Free
- Soy-Free
- Nut-Free
- No GMOs
- Vegan
Certified for Peace of Mind:
- FODMAP Friendly Certified
- Halal Certified
- Kosher Certified
What Our Customers Say
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Dairy-Free
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Gluten-Free
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No GMOs
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Soy-Free
VSL#3" Benefits:
A Clinically Studied Medical Food
VSL#3® is a medical-grade formulation supported byclinical research.
Ultra-High Potency, Guaranteed
Contains 112.5 billion live bacteria (CFU) per capsule-an ultra-high-potency formula designed to keep itslabeled potency through expiration when stored underrecommended conditions.
Multi-Strain
8 complementary strains from 3 different genera.
The VSL® Probiotics Difference
Medical Foods & Supplements
From medical foods formulated forthe dietary management of Glconditions to supplements for dailywellness, VSL® Probiotics is made tothe highest standards of quality and
consistency
Proven Potency
Up to 900 billion live bacteria perserving-verified to maintainlabeled CFU counts throughexpiration when stored asrecommended.
Evidence-Based Formulations
Formulated with probiotic strainsand combinations supported bypublished research and guided bymicrobiome science.
Trusted by Professionals
Rooted in the heritage of VSL#3®-probiotic trusted by healthcareprofessionals-VSL® Probioticscarries that same dedication toquality and research into every new
formulation.
FAQs
What is VSL#3®?
What is VSL#3®?
VSL#3®is an ultra-high-potency probiotic medical food intended for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and an ileal pouch (pouchitis).
How should I store VSL#3®?
How should I store VSL#3®?
VSL#3®should be stored under refrigeration at 36–46°F (2–8°C) to preserve potency. It can remain at room temperature for up to 2 weeks without reducing effectiveness.
What is a Medical Food?
What is a Medical Food?
Medical foods are formulated for the dietary management of diseases or conditions with distinctive nutritional needs that cannot be met by diet alone. Unlike dietary supplements, medical foods are intended for use under a healthcare provider's supervision.
How does VSL#3® compare to a Low FODMAP diet for IBS management?
How does VSL#3® compare to a Low FODMAP diet for IBS management?
In a 2021 clinical study, VSL#3®demonstrated dietary management outcomes in people with IBS comparable to those achieved with a low FODMAP diet¹ — a commonly recommended but restrictive approach. Because VSL#3®is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.
1Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291.
How are VSL#3® and VSL4® Gut different?
How are VSL#3® and VSL4® Gut different?
Although both products contain the same 8 probiotic strains, they are formulated and labeled for different purposes. VSL#3®is a refrigerated, ultra-high-potency probiotic medical food for the dietary management of specific GI conditions. VSL4®Gut is a probiotic supplement designed to support digestive comfort, regularity, and overall gut health.*